Reviews Aminosyn II 5% in 25% Dextrose


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Aminosyn II 5% in 25% Dextrose Drug Description
AMINOSYN® II 5%
in 25% Dextrose Injection
AN AMINO ACID INJECTION IN DEXTROSE INJECTION
NOTE: These solutions are hypertonic. See WARNINGS
and PRECAUTIONS.
Nutrimix® Dual-chamber Flexible Container
The Upper Chamber Contains 500 mL of Aminosyn II 10% (An Amino Acid Injection)

The Lower Chamber Contains 500 mL of 50% Dextrose Injection, USP
DRUG DESCRIPTION
Upper Chamber: Contains 500 mL of Aminosyn II 10% (an amino acid injection)
— a sterile, nonpyrogenic solution for intravenous infusion. The formulation
is described in the table below.
Lower Chamber: Contains 500 mL of 50% Dextrose Injection, USP — a sterile,
nonpyrogenic, hypertonic solution of Dextrose, USP in water for injection. The
table below indicates the characteristics of this concentrated solution.
The container must be used only after removing the clamp and thoroughly mixing
the contents of the two chambers. The solution resulting from mixing the contents
of the upper and lower chamber contains 5% amino acids in 25% dextrose. Mixing
the contents of the upper and lower chambers yields a concentrated source of
amino acids and carbohydrate calories for intravenous infusion. Headspace contains
Nitrogen gas. The composition of this admixture is described in the table below.




 
Solution Composition per 100 mL


Upper
Chamber
Lower
Chamber
Admixture


Dextrose, hydrous (g)
 
50
25


Essential Amino Acids (mg)


  Isoleucine
660
 
330


  Leucine
1000
 
500


  Lysine (as acetate salt)*
1050
 
525


  Methionine
172
 
86


  Phenylalanine
298
 
149


  Threonine
400
 
200


  Tryptophan
200
 
100


  Valine
500
 
250


Nonessential Amino Acids (mg)


  Alanine
993
 
496


  Arginine
1018
 
509


  L-Aspartic Acid
700
 
350


  L-Glutamic Acid
738
 
369


  Glycine
500
 
250


  Histidine
300
 
150


  Proline
722
 
361


  Serine
530
 
265


  N-Acetyl-L-Tyrosine
270
 
135


  Total Amino Acids (g)
10
 
5


  Protein Equivalent (g)
10
 
5


  Total Nitrogen (g)
1.53
 
0.77


Electrolytes (mEq/liter)


  Sodiuma(Na+)
44.4
 
22.2


  Acetateb(C2H3O2–)
71.8
 
35.9


  Sodium hydrosulfite (mg/100 mL)
60
 
30


Osmolarity mOsmol/liter (actual)
868
1997
1539


pH
5.8
4.3
5.8


rangec
5.0 to 6.5
3.2 to 6.5
5.0 to 6.5


*Amount cited is for lysine alone and does
not include the acetate salt.
a Includes sodium from the pH adjustor (sodium hydroxide) and
the antioxidant, sodium hydrosulfite.
b From lysine acetate.
c Contains sodium hydroxide for pH adjustment.




The formulas for the individual amino acids are as follows:



Essential Amino Acids


Isoleucine
CH3CH2CH(CH3)CH(NH2)COOH


Leucine
(CH3)2CHCH2CH(NH2)COOH


Lysine Acetate
H2N(CH2)4CH(NH2)COOH • CH3COOH


Methionine
CH3S(CH2)2CH(NH2)COOH


Phenylalanine



CH2CH(NH2)COOH




Threonine
CH3CH(OH)CH(NH2)COOH


Tryptophan



CH2CH(NH2)COOH




Valine
(CH3)2CHCH(NH2)COOH


Nonessential Amino Acids


Alanine
CH3CH(NH2)COOH


Arginine
H2NC(NH)NH(CH2)3CH(NH2)COOH


L-Aspartic Acid
HOOCCH2CH(NH2)COOH


L-Glutamic Acid
HOOC(CH2)2CH(NH2)COOH


Glycine
H2NCH2COOH


Histidine



CH2CH(NH2)COOH




Proline







Serine
HOCH2CH(NH2)COOH


N-Acetyl-L-Tyrosine








Dextrose, USP is chemically designated D-glucose, monohydrate (C6H12O6
•H20), a hexose sugar freely soluble in water.
The flexible plastic container is fabricated from a specially formulated nonplasticized
thermoplastic co-polyester (CR3). Water can permeate from inside the container
into the overwrap but not in amounts sufficient to affect the solution significantly.
Solutions inside the plastic container also can leach out certain of its chemical
components in very small amounts before the expiration period is attained. However,
the safety of the plastic has been confirmed by tests in animals according to
USP biological standards for plastic containers.Last reviewed on RxList: 1/14/2009




Aminosyn II 5% in 25% Dextrose Drug Description
AMINOSYN® II 5%
in 25% Dextrose Injection
AN AMINO ACID INJECTION IN DEXTROSE INJECTION
NOTE: These solutions are hypertonic. See WARNINGS
and PRECAUTIONS.
Nutrimix® Dual-chamber Flexible Container
The Upper Chamber Contains 500 mL of Aminosyn II 10% (An Amino Acid Injection)

The Lower Chamber Contains 500 mL of 50% Dextrose Injection, USP
DRUG DESCRIPTION
Upper Chamber: Contains 500 mL of Aminosyn II 10% (an amino acid injection)
— a sterile, nonpyrogenic solution for intravenous infusion. The formulation
is described in the table below.
Lower Chamber: Contains 500 mL of 50% Dextrose Injection, USP — a sterile,
nonpyrogenic, hypertonic solution of Dextrose, USP in water for injection. The
table below indicates the characteristics of this concentrated solution.
The container must be used only after removing the clamp and thoroughly mixing
the contents of the two chambers. The solution resulting from mixing the contents
of the upper and lower chamber contains 5% amino acids in 25% dextrose. Mixing
the contents of the upper and lower chambers yields a concentrated source of
amino acids and carbohydrate calories for intravenous infusion. Headspace contains
Nitrogen gas. The composition of this admixture is described in the table below.




 
Solution Composition per 100 mL


Upper
Chamber
Lower
Chamber
Admixture


Dextrose, hydrous (g)
 
50
25


Essential Amino Acids (mg)


  Isoleucine
660
 
330


  Leucine
1000
 
500


  Lysine (as acetate salt)*
1050
 
525


  Methionine
172
 
86


  Phenylalanine
298
 
149


  Threonine
400
 
200


  Tryptophan
200
 
100


  Valine
500
 
250


Nonessential Amino Acids (mg)


  Alanine
993
 
496


  Arginine
1018
 
509


  L-Aspartic Acid
700
 
350


  L-Glutamic Acid
738
 
369


  Glycine
500
 
250


  Histidine
300
 
150


  Proline
722
 
361


  Serine
530
 
265


  N-Acetyl-L-Tyrosine
270
 
135


  Total Amino Acids (g)
10
 
5


  Protein Equivalent (g)
10
 
5


  Total Nitrogen (g)
1.53
 
0.77


Electrolytes (mEq/liter)


  Sodiuma(Na+)
44.4
 
22.2


  Acetateb(C2H3O2–)
71.8
 
35.9


  Sodium hydrosulfite (mg/100 mL)
60
 
30


Osmolarity mOsmol/liter (actual)
868
1997
1539


pH
5.8
4.3
5.8


rangec
5.0 to 6.5
3.2 to 6.5
5.0 to 6.5


*Amount cited is for lysine alone and does
not include the acetate salt.
a Includes sodium from the pH adjustor (sodium hydroxide) and
the antioxidant, sodium hydrosulfite.
b From lysine acetate.
c Contains sodium hydroxide for pH adjustment.




The formulas for the individual amino acids are as follows:



Essential Amino Acids


Isoleucine
CH3CH2CH(CH3)CH(NH2)COOH


Leucine
(CH3)2CHCH2CH(NH2)COOH


Lysine Acetate
H2N(CH2)4CH(NH2)COOH • CH3COOH


Methionine
CH3S(CH2)2CH(NH2)COOH


Phenylalanine



CH2CH(NH2)COOH




Threonine
CH3CH(OH)CH(NH2)COOH


Tryptophan



CH2CH(NH2)COOH




Valine
(CH3)2CHCH(NH2)COOH


Nonessential Amino Acids


Alanine
CH3CH(NH2)COOH


Arginine
H2NC(NH)NH(CH2)3CH(NH2)COOH


L-Aspartic Acid
HOOCCH2CH(NH2)COOH


L-Glutamic Acid
HOOC(CH2)2CH(NH2)COOH


Glycine
H2NCH2COOH


Histidine



CH2CH(NH2)COOH




Proline







Serine
HOCH2CH(NH2)COOH


N-Acetyl-L-Tyrosine








Dextrose, USP is chemically designated D-glucose, monohydrate (C6H12O6
•H20), a hexose sugar freely soluble in water.
The flexible plastic container is fabricated from a specially formulated nonplasticized
thermoplastic co-polyester (CR3). Water can permeate from inside the container
into the overwrap but not in amounts sufficient to affect the solution significantly.
Solutions inside the plastic container also can leach out certain of its chemical
components in very small amounts before the expiration period is attained. However,
the safety of the plastic has been confirmed by tests in animals according to
USP biological standards for plastic containers.Last reviewed on RxList: 1/14/2009




Aminosyn II 5% in 25% Dextrose Drug Description
AMINOSYN® II 5%
in 25% Dextrose Injection
AN AMINO ACID INJECTION IN DEXTROSE INJECTION
NOTE: These solutions are hypertonic. See WARNINGS
and PRECAUTIONS.
Nutrimix® Dual-chamber Flexible Container
The Upper Chamber Contains 500 mL of Aminosyn II 10% (An Amino Acid Injection)

The Lower Chamber Contains 500 mL of 50% Dextrose Injection, USP
DRUG DESCRIPTION
Upper Chamber: Contains 500 mL of Aminosyn II 10% (an amino acid injection)
— a sterile, nonpyrogenic solution for intravenous infusion. The formulation
is described in the table below.
Lower Chamber: Contains 500 mL of 50% Dextrose Injection, USP — a sterile,
nonpyrogenic, hypertonic solution of Dextrose, USP in water for injection. The
table below indicates the characteristics of this concentrated solution.
The container must be used only after removing the clamp and thoroughly mixing
the contents of the two chambers. The solution resulting from mixing the contents
of the upper and lower chamber contains 5% amino acids in 25% dextrose. Mixing
the contents of the upper and lower chambers yields a concentrated source of
amino acids and carbohydrate calories for intravenous infusion. Headspace contains
Nitrogen gas. The composition of this admixture is described in the table below.




 
Solution Composition per 100 mL


Upper
Chamber
Lower
Chamber
Admixture


Dextrose, hydrous (g)
 
50
25


Essential Amino Acids (mg)


  Isoleucine
660
 
330


  Leucine
1000
 
500


  Lysine (as acetate salt)*
1050
 
525


  Methionine
172
 
86


  Phenylalanine
298
 
149


  Threonine
400
 
200


  Tryptophan
200
 
100


  Valine
500
 
250


Nonessential Amino Acids (mg)


  Alanine
993
 
496


  Arginine
1018
 
509


  L-Aspartic Acid
700
 
350


  L-Glutamic Acid
738
 
369


  Glycine
500
 
250


  Histidine
300
 
150


  Proline
722
 
361


  Serine
530
 
265


  N-Acetyl-L-Tyrosine
270
 
135


  Total Amino Acids (g)
10
 
5


  Protein Equivalent (g)
10
 
5


  Total Nitrogen (g)
1.53
 
0.77


Electrolytes (mEq/liter)


  Sodiuma(Na+)
44.4
 
22.2


  Acetateb(C2H3O2–)
71.8
 
35.9


  Sodium hydrosulfite (mg/100 mL)
60
 
30


Osmolarity mOsmol/liter (actual)
868
1997
1539


pH
5.8
4.3
5.8


rangec
5.0 to 6.5
3.2 to 6.5
5.0 to 6.5


*Amount cited is for lysine alone and does
not include the acetate salt.
a Includes sodium from the pH adjustor (sodium hydroxide) and
the antioxidant, sodium hydrosulfite.
b From lysine acetate.
c Contains sodium hydroxide for pH adjustment.




The formulas for the individual amino acids are as follows:



Essential Amino Acids


Isoleucine
CH3CH2CH(CH3)CH(NH2)COOH


Leucine
(CH3)2CHCH2CH(NH2)COOH


Lysine Acetate
H2N(CH2)4CH(NH2)COOH • CH3COOH


Methionine
CH3S(CH2)2CH(NH2)COOH


Phenylalanine



CH2CH(NH2)COOH




Threonine
CH3CH(OH)CH(NH2)COOH


Tryptophan



CH2CH(NH2)COOH




Valine
(CH3)2CHCH(NH2)COOH


Nonessential Amino Acids


Alanine
CH3CH(NH2)COOH


Arginine
H2NC(NH)NH(CH2)3CH(NH2)COOH


L-Aspartic Acid
HOOCCH2CH(NH2)COOH


L-Glutamic Acid
HOOC(CH2)2CH(NH2)COOH


Glycine
H2NCH2COOH


Histidine



CH2CH(NH2)COOH




Proline







Serine
HOCH2CH(NH2)COOH


N-Acetyl-L-Tyrosine








Dextrose, USP is chemically designated D-glucose, monohydrate (C6H12O6
•H20), a hexose sugar freely soluble in water.
The flexible plastic container is fabricated from a specially formulated nonplasticized
thermoplastic co-polyester (CR3). Water can permeate from inside the container
into the overwrap but not in amounts sufficient to affect the solution significantly.
Solutions inside the plastic container also can leach out certain of its chemical
components in very small amounts before the expiration period is attained. However,
the safety of the plastic has been confirmed by tests in animals according to
USP biological standards for plastic containers.Last reviewed on RxList: 1/14/2009




Aminosyn II 5% in 25% Dextrose Drug Description
AMINOSYN® II 5%
in 25% Dextrose Injection
AN AMINO ACID INJECTION IN DEXTROSE INJECTION
NOTE: These solutions are hypertonic. See WARNINGS
and PRECAUTIONS.
Nutrimix® Dual-chamber Flexible Container
The Upper Chamber Contains 500 mL of Aminosyn II 10% (An Amino Acid Injection)

The Lower Chamber Contains 500 mL of 50% Dextrose Injection, USP
DRUG DESCRIPTION
Upper Chamber: Contains 500 mL of Aminosyn II 10% (an amino acid injection)
— a sterile, nonpyrogenic solution for intravenous infusion. The formulation
is described in the table below.
Lower Chamber: Contains 500 mL of 50% Dextrose Injection, USP — a sterile,
nonpyrogenic, hypertonic solution of Dextrose, USP in water for injection. The
table below indicates the characteristics of this concentrated solution.
The container must be used only after removing the clamp and thoroughly mixing
the contents of the two chambers. The solution resulting from mixing the contents
of the upper and lower chamber contains 5% amino acids in 25% dextrose. Mixing
the contents of the upper and lower chambers yields a concentrated source of
amino acids and carbohydrate calories for intravenous infusion. Headspace contains
Nitrogen gas. The composition of this admixture is described in the table below.




 
Solution Composition per 100 mL


Upper
Chamber
Lower
Chamber
Admixture


Dextrose, hydrous (g)
 
50
25


Essential Amino Acids (mg)


  Isoleucine
660
 
330


  Leucine
1000
 
500


  Lysine (as acetate salt)*
1050
 
525


  Methionine
172
 
86


  Phenylalanine
298
 
149


  Threonine
400
 
200


  Tryptophan
200
 
100


  Valine
500
 
250


Nonessential Amino Acids (mg)


  Alanine
993
 
496


  Arginine
1018
 
509


  L-Aspartic Acid
700
 
350


  L-Glutamic Acid
738
 
369


  Glycine
500
 
250


  Histidine
300
 
150


  Proline
722
 
361


  Serine
530
 
265


  N-Acetyl-L-Tyrosine
270
 
135


  Total Amino Acids (g)
10
 
5


  Protein Equivalent (g)
10
 
5


  Total Nitrogen (g)
1.53
 
0.77


Electrolytes (mEq/liter)


  Sodiuma(Na+)
44.4
 
22.2


  Acetateb(C2H3O2–)
71.8
 
35.9


  Sodium hydrosulfite (mg/100 mL)
60
 
30


Osmolarity mOsmol/liter (actual)
868
1997
1539


pH
5.8
4.3
5.8


rangec
5.0 to 6.5
3.2 to 6.5
5.0 to 6.5


*Amount cited is for lysine alone and does
not include the acetate salt.
a Includes sodium from the pH adjustor (sodium hydroxide) and
the antioxidant, sodium hydrosulfite.
b From lysine acetate.
c Contains sodium hydroxide for pH adjustment.




The formulas for the individual amino acids are as follows:



Essential Amino Acids


Isoleucine
CH3CH2CH(CH3)CH(NH2)COOH


Leucine
(CH3)2CHCH2CH(NH2)COOH


Lysine Acetate
H2N(CH2)4CH(NH2)COOH • CH3COOH


Methionine
CH3S(CH2)2CH(NH2)COOH


Phenylalanine



CH2CH(NH2)COOH




Threonine
CH3CH(OH)CH(NH2)COOH


Tryptophan



CH2CH(NH2)COOH




Valine
(CH3)2CHCH(NH2)COOH


Nonessential Amino Acids


Alanine
CH3CH(NH2)COOH


Arginine
H2NC(NH)NH(CH2)3CH(NH2)COOH


L-Aspartic Acid
HOOCCH2CH(NH2)COOH


L-Glutamic Acid
HOOC(CH2)2CH(NH2)COOH


Glycine
H2NCH2COOH


Histidine



CH2CH(NH2)COOH




Proline







Serine
HOCH2CH(NH2)COOH


N-Acetyl-L-Tyrosine








Dextrose, USP is chemically designated D-glucose, monohydrate (C6H12O6
•H20), a hexose sugar freely soluble in water.
The flexible plastic container is fabricated from a specially formulated nonplasticized
thermoplastic co-polyester (CR3). Water can permeate from inside the container
into the overwrap but not in amounts sufficient to affect the solution significantly.
Solutions inside the plastic container also can leach out certain of its chemical
components in very small amounts before the expiration period is attained. However,
the safety of the plastic has been confirmed by tests in animals according to
USP biological standards for plastic containers.Last reviewed on RxList: 1/14/2009




Aminosyn II 5% in 25% Dextrose Drug Description
AMINOSYN® II 5%
in 25% Dextrose Injection
AN AMINO ACID INJECTION IN DEXTROSE INJECTION
NOTE: These solutions are hypertonic. See WARNINGS
and PRECAUTIONS.
Nutrimix® Dual-chamber Flexible Container
The Upper Chamber Contains 500 mL of Aminosyn II 10% (An Amino Acid Injection)

The Lower Chamber Contains 500 mL of 50% Dextrose Injection, USP
DRUG DESCRIPTION
Upper Chamber: Contains 500 mL of Aminosyn II 10% (an amino acid injection)
— a sterile, nonpyrogenic solution for intravenous infusion. The formulation
is described in the table below.
Lower Chamber: Contains 500 mL of 50% Dextrose Injection, USP — a sterile,
nonpyrogenic, hypertonic solution of Dextrose, USP in water for injection. The
table below indicates the characteristics of this concentrated solution.
The container must be used only after removing the clamp and thoroughly mixing
the contents of the two chambers. The solution resulting from mixing the contents
of the upper and lower chamber contains 5% amino acids in 25% dextrose. Mixing
the contents of the upper and lower chambers yields a concentrated source of
amino acids and carbohydrate calories for intravenous infusion. Headspace contains
Nitrogen gas. The composition of this admixture is described in the table below.




 
Solution Composition per 100 mL


Upper
Chamber
Lower
Chamber
Admixture


Dextrose, hydrous (g)
 
50
25


Essential Amino Acids (mg)


  Isoleucine
660
 
330


  Leucine
1000
 
500


  Lysine (as acetate salt)*
1050
 
525


  Methionine
172
 
86


  Phenylalanine
298
 
149


  Threonine
400
 
200


  Tryptophan
200
 
100


  Valine
500
 
250


Nonessential Amino Acids (mg)


  Alanine
993
 
496


  Arginine
1018
 
509


  L-Aspartic Acid
700
 
350


  L-Glutamic Acid
738
 
369


  Glycine
500
 
250


  Histidine
300
 
150


  Proline
722
 
361


  Serine
530
 
265


  N-Acetyl-L-Tyrosine
270
 
135


  Total Amino Acids (g)
10
 
5


  Protein Equivalent (g)
10
 
5


  Total Nitrogen (g)
1.53
 
0.77


Electrolytes (mEq/liter)


  Sodiuma(Na+)
44.4
 
22.2


  Acetateb(C2H3O2–)
71.8
 
35.9


  Sodium hydrosulfite (mg/100 mL)
60
 
30


Osmolarity mOsmol/liter (actual)
868
1997
1539


pH
5.8
4.3
5.8


rangec
5.0 to 6.5
3.2 to 6.5
5.0 to 6.5


*Amount cited is for lysine alone and does
not include the acetate salt.
a Includes sodium from the pH adjustor (sodium hydroxide) and
the antioxidant, sodium hydrosulfite.
b From lysine acetate.
c Contains sodium hydroxide for pH adjustment.




The formulas for the individual amino acids are as follows:



Essential Amino Acids


Isoleucine
CH3CH2CH(CH3)CH(NH2)COOH


Leucine
(CH3)2CHCH2CH(NH2)COOH


Lysine Acetate
H2N(CH2)4CH(NH2)COOH • CH3COOH


Methionine
CH3S(CH2)2CH(NH2)COOH


Phenylalanine



CH2CH(NH2)COOH




Threonine
CH3CH(OH)CH(NH2)COOH


Tryptophan



CH2CH(NH2)COOH




Valine
(CH3)2CHCH(NH2)COOH


Nonessential Amino Acids


Alanine
CH3CH(NH2)COOH


Arginine
H2NC(NH)NH(CH2)3CH(NH2)COOH


L-Aspartic Acid
HOOCCH2CH(NH2)COOH


L-Glutamic Acid
HOOC(CH2)2CH(NH2)COOH


Glycine
H2NCH2COOH


Histidine



CH2CH(NH2)COOH




Proline







Serine
HOCH2CH(NH2)COOH


N-Acetyl-L-Tyrosine








Dextrose, USP is chemically designated D-glucose, monohydrate (C6H12O6
•H20), a hexose sugar freely soluble in water.
The flexible plastic container is fabricated from a specially formulated nonplasticized
thermoplastic co-polyester (CR3). Water can permeate from inside the container
into the overwrap but not in amounts sufficient to affect the solution significantly.
Solutions inside the plastic container also can leach out certain of its chemical
components in very small amounts before the expiration period is attained. However,
the safety of the plastic has been confirmed by tests in animals according to
USP biological standards for plastic containers.Last reviewed on RxList: 1/14/2009





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1 This information intended for U.S. residents only. ©Hospira, 2006 Hospira, Inc., Lake Forest, IL 60045 USA Reference EN-0130 AN AMINO ACID INJECTION WITH MAINTENANCE ... Aminosyn®II 3.5% M and 4.25% M in Dextrose Injection


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Reviews Lactated Ringer's and 5% Dextrose Injection

Lactated Ringer's in 5% Dextrose Drug Description Lactated Ringer's and 5% Dextrose Injection, USP in VIAFLEX Plastic Container DRUG DESCRIPTION Lactated Ringer's and 5% Dextrose Injection, USP is a sterile, nonpyrogenic solution for...
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Reviews Chloroquine

Aralen Drug Description ARALEN® (chloroquine phosphate, USP) For Malaria and Extraintestinal Amebiasis DRUG DESCRIPTION What are the possible side effects of chloroquine (Aralen Phosphate)? Stop taking chloroquine and seek...
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Reviews Ibuprofen

Motrin Drug Description MOTRIN® (ibuprofen) Tablets, USP Cardiovascular Risk NSAIDs may cause an increased risk of serious cardiovascular thrombotic events, myocardial infarction, and stroke, which can be fatal. This risk...
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Reviews Wellbutrin XL

Wellbutrin XL Drug Description WELLBUTRIN XL® (bupropion hydrochloride) Extended-Release Tablets WARNING Suicidality and Antidepressant Drugs Use in Treating Psychiatric Disorders: Antidepressants increased the risk compared...
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Reviews Ondansetron Hydrochloride

Zofran Drug Description ZOFRAN® (ondansetron hydrochloride) Tablets ZOFRAN ODT® (ondansetron) Orally Disintegrating Tablets ZOFRAN® (ondansetron hydrochloride) Oral Solution DRUG DESCRIPTION What are the...
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