Reviews Adagen


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Adagen Drug Description
ADAGEN®
(pegademase bovine) Injection
DRUG DESCRIPTION



What are the possible side effects of pegademase bovine (Adagen)?

If you experience any of the following serious side effects, stop using the pegademase bovine and seek emergency medical treatment or contact your doctor immediately:

an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives); or
signs of infection such as sore throat, fever or congestion.

Other, less serious side effects may be more likely to occur. Continue to use the pegademase bovine and talk to your doctor...
Read All Potential Side Effects for Adagen »




ADAGEN® (pegademase bovine) Injection is a modified enzyme used
for enzyme replacement therapy for the treatment of severe combined immunodeficiency
disease (SCID) associated with a deficiency of adenosine deaminase.
ADAGEN® (pegademase bovine) Injection is supplied in an isotonic, pyrogen free, sterile solution, pH 7.2-7.4, for intramuscular injection only. The solution is clear and colorless. It is supplied in 1.5 mL single-dose vials.
The chemical name for ADAGEN® (pegademase bovine) Injection is (monomethoxypolyethylene glycol succinimidyl) 11-17┬şadenosine deaminase. It is a conjugate of numerous strands of monomethoxypolyethylene glycol (PEG), molecular weight 5,000, covalently attached to the enzyme adenosine deaminase (ADA). ADA (adenosine deaminase EC 3.5.4.4) used in the manufacture of ADAGEN® (pegademase bovine) Injection is derived from bovine intestine.
The structural formula of ADAGEN® (pegademase bovine) Injection is:








x ≈ 114 oxyethylene groups per PEG strand.
y ≈ 11-17 primary amino groups of lysine onto which succinyl PEG is attached.
Each milliliter of ADAGEN® (pegademase bovine) Injection contains:
Pegademase bovine.............................250 units*
Monobasic sodium phosphate, USP.............................1.20 mg
Dibasic sodium phosphate, USP.............................5.58 mg
Sodium Chloride, USP.............................8.50 mg
Water for injection, USP.............................q.s. to 1.0 mL
*One unit of activity is defined as the amount of ADA that converts 1┬ÁM of
adenosine to inosine per minute at 25┬░C and pH 7.3.Last reviewed on RxList: 12/4/2008




Adagen Drug Description
ADAGEN®
(pegademase bovine) Injection
DRUG DESCRIPTION



What are the possible side effects of pegademase bovine (Adagen)?

If you experience any of the following serious side effects, stop using the pegademase bovine and seek emergency medical treatment or contact your doctor immediately:

an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives); or
signs of infection such as sore throat, fever or congestion.

Other, less serious side effects may be more likely to occur. Continue to use the pegademase bovine and talk to your doctor...
Read All Potential Side Effects for Adagen »




ADAGEN® (pegademase bovine) Injection is a modified enzyme used
for enzyme replacement therapy for the treatment of severe combined immunodeficiency
disease (SCID) associated with a deficiency of adenosine deaminase.
ADAGEN® (pegademase bovine) Injection is supplied in an isotonic, pyrogen free, sterile solution, pH 7.2-7.4, for intramuscular injection only. The solution is clear and colorless. It is supplied in 1.5 mL single-dose vials.
The chemical name for ADAGEN® (pegademase bovine) Injection is (monomethoxypolyethylene glycol succinimidyl) 11-17┬şadenosine deaminase. It is a conjugate of numerous strands of monomethoxypolyethylene glycol (PEG), molecular weight 5,000, covalently attached to the enzyme adenosine deaminase (ADA). ADA (adenosine deaminase EC 3.5.4.4) used in the manufacture of ADAGEN® (pegademase bovine) Injection is derived from bovine intestine.
The structural formula of ADAGEN® (pegademase bovine) Injection is:








x ≈ 114 oxyethylene groups per PEG strand.
y ≈ 11-17 primary amino groups of lysine onto which succinyl PEG is attached.
Each milliliter of ADAGEN® (pegademase bovine) Injection contains:
Pegademase bovine.............................250 units*
Monobasic sodium phosphate, USP.............................1.20 mg
Dibasic sodium phosphate, USP.............................5.58 mg
Sodium Chloride, USP.............................8.50 mg
Water for injection, USP.............................q.s. to 1.0 mL
*One unit of activity is defined as the amount of ADA that converts 1┬ÁM of
adenosine to inosine per minute at 25┬░C and pH 7.3.Last reviewed on RxList: 12/4/2008




Adagen Drug Description
ADAGEN®
(pegademase bovine) Injection
DRUG DESCRIPTION



What are the possible side effects of pegademase bovine (Adagen)?

If you experience any of the following serious side effects, stop using the pegademase bovine and seek emergency medical treatment or contact your doctor immediately:

an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives); or
signs of infection such as sore throat, fever or congestion.

Other, less serious side effects may be more likely to occur. Continue to use the pegademase bovine and talk to your doctor...
Read All Potential Side Effects for Adagen »




ADAGEN® (pegademase bovine) Injection is a modified enzyme used
for enzyme replacement therapy for the treatment of severe combined immunodeficiency
disease (SCID) associated with a deficiency of adenosine deaminase.
ADAGEN® (pegademase bovine) Injection is supplied in an isotonic, pyrogen free, sterile solution, pH 7.2-7.4, for intramuscular injection only. The solution is clear and colorless. It is supplied in 1.5 mL single-dose vials.
The chemical name for ADAGEN® (pegademase bovine) Injection is (monomethoxypolyethylene glycol succinimidyl) 11-17┬şadenosine deaminase. It is a conjugate of numerous strands of monomethoxypolyethylene glycol (PEG), molecular weight 5,000, covalently attached to the enzyme adenosine deaminase (ADA). ADA (adenosine deaminase EC 3.5.4.4) used in the manufacture of ADAGEN® (pegademase bovine) Injection is derived from bovine intestine.
The structural formula of ADAGEN® (pegademase bovine) Injection is:








x ≈ 114 oxyethylene groups per PEG strand.
y ≈ 11-17 primary amino groups of lysine onto which succinyl PEG is attached.
Each milliliter of ADAGEN® (pegademase bovine) Injection contains:
Pegademase bovine.............................250 units*
Monobasic sodium phosphate, USP.............................1.20 mg
Dibasic sodium phosphate, USP.............................5.58 mg
Sodium Chloride, USP.............................8.50 mg
Water for injection, USP.............................q.s. to 1.0 mL
*One unit of activity is defined as the amount of ADA that converts 1┬ÁM of
adenosine to inosine per minute at 25┬░C and pH 7.3.Last reviewed on RxList: 12/4/2008




Adagen Drug Description
ADAGEN®
(pegademase bovine) Injection
DRUG DESCRIPTION



What are the possible side effects of pegademase bovine (Adagen)?

If you experience any of the following serious side effects, stop using the pegademase bovine and seek emergency medical treatment or contact your doctor immediately:

an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives); or
signs of infection such as sore throat, fever or congestion.

Other, less serious side effects may be more likely to occur. Continue to use the pegademase bovine and talk to your doctor...
Read All Potential Side Effects for Adagen »




ADAGEN® (pegademase bovine) Injection is a modified enzyme used
for enzyme replacement therapy for the treatment of severe combined immunodeficiency
disease (SCID) associated with a deficiency of adenosine deaminase.
ADAGEN® (pegademase bovine) Injection is supplied in an isotonic, pyrogen free, sterile solution, pH 7.2-7.4, for intramuscular injection only. The solution is clear and colorless. It is supplied in 1.5 mL single-dose vials.
The chemical name for ADAGEN® (pegademase bovine) Injection is (monomethoxypolyethylene glycol succinimidyl) 11-17┬şadenosine deaminase. It is a conjugate of numerous strands of monomethoxypolyethylene glycol (PEG), molecular weight 5,000, covalently attached to the enzyme adenosine deaminase (ADA). ADA (adenosine deaminase EC 3.5.4.4) used in the manufacture of ADAGEN® (pegademase bovine) Injection is derived from bovine intestine.
The structural formula of ADAGEN® (pegademase bovine) Injection is:








x ≈ 114 oxyethylene groups per PEG strand.
y ≈ 11-17 primary amino groups of lysine onto which succinyl PEG is attached.
Each milliliter of ADAGEN® (pegademase bovine) Injection contains:
Pegademase bovine.............................250 units*
Monobasic sodium phosphate, USP.............................1.20 mg
Dibasic sodium phosphate, USP.............................5.58 mg
Sodium Chloride, USP.............................8.50 mg
Water for injection, USP.............................q.s. to 1.0 mL
*One unit of activity is defined as the amount of ADA that converts 1┬ÁM of
adenosine to inosine per minute at 25┬░C and pH 7.3.Last reviewed on RxList: 12/4/2008




Adagen Drug Description
ADAGEN®
(pegademase bovine) Injection
DRUG DESCRIPTION



What are the possible side effects of pegademase bovine (Adagen)?

If you experience any of the following serious side effects, stop using the pegademase bovine and seek emergency medical treatment or contact your doctor immediately:

an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives); or
signs of infection such as sore throat, fever or congestion.

Other, less serious side effects may be more likely to occur. Continue to use the pegademase bovine and talk to your doctor...
Read All Potential Side Effects for Adagen »




ADAGEN® (pegademase bovine) Injection is a modified enzyme used
for enzyme replacement therapy for the treatment of severe combined immunodeficiency
disease (SCID) associated with a deficiency of adenosine deaminase.
ADAGEN® (pegademase bovine) Injection is supplied in an isotonic, pyrogen free, sterile solution, pH 7.2-7.4, for intramuscular injection only. The solution is clear and colorless. It is supplied in 1.5 mL single-dose vials.
The chemical name for ADAGEN® (pegademase bovine) Injection is (monomethoxypolyethylene glycol succinimidyl) 11-17┬şadenosine deaminase. It is a conjugate of numerous strands of monomethoxypolyethylene glycol (PEG), molecular weight 5,000, covalently attached to the enzyme adenosine deaminase (ADA). ADA (adenosine deaminase EC 3.5.4.4) used in the manufacture of ADAGEN® (pegademase bovine) Injection is derived from bovine intestine.
The structural formula of ADAGEN® (pegademase bovine) Injection is:








x ≈ 114 oxyethylene groups per PEG strand.
y ≈ 11-17 primary amino groups of lysine onto which succinyl PEG is attached.
Each milliliter of ADAGEN® (pegademase bovine) Injection contains:
Pegademase bovine.............................250 units*
Monobasic sodium phosphate, USP.............................1.20 mg
Dibasic sodium phosphate, USP.............................5.58 mg
Sodium Chloride, USP.............................8.50 mg
Water for injection, USP.............................q.s. to 1.0 mL
*One unit of activity is defined as the amount of ADA that converts 1┬ÁM of
adenosine to inosine per minute at 25┬░C and pH 7.3.Last reviewed on RxList: 12/4/2008





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Other reviews about Adagen on web:

Learn about the prescription medication Adagen (Pegademase Bovine), drug uses, dosage, side effects, drug interactions, warnings, reviews and patient labeling. Adagen (Pegademase Bovine) Drug Information: Uses, Side Effects ...


ADAGEN ® (pegademase bovine) Injection is used to treat patients afflicted with a type of Severe Combined Immunodeficiency Disease (also known as SCID or the "Bubble Boy Disease ... Adagen


All about Adagen. View complete and up to date Adagen information - part of the Drugs.com trusted medication database. Adagen Facts and Comparisons at Drugs.com


Accurate, FDA approved Adagen information for healthcare professionals and patients - brought to you by Drugs.com. Adagen Official FDA information, side effects and uses.


The only enzyme replacement therapy for patients with ADA-deficient Severe Combined Immunodeficiency Disease; A life-saving treatment that provides predictable immune function ... Adagen


Adagen Medical company profile in Atlanta, GA. Our free company profile report for Adagen Medical includes business information such as contact, sales and financial data. Adagen Medical (Adagen Medical International, Inc) - Atlanta ...


Learn about Adagen (Pegademase Bovine) - Side Effects, Drug Interactions, Pictures, Patient Information on RxList Adagen (Pegademase Bovine) Patient Drug Information and Side ...


DESCRIPTION ADAGEN ® (pegademase bovine) Injection is a modified enzyme used for enzyme replacement therapy for the treatment of severe combined immunodeficiency disease (SCID ... ADAGEN® (pegademase bovine) Injection


Find patient medical information for Adagen IM on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. Adagen IM : Uses, Side Effects, Interactions, Pictures, Warnings ...


Adagen - Pegademase bovine is the enzyme called adenosine deaminase (ADA). Without ADA, certain proteins accumulate that harm white blood cells. White blood cells are important for ... Adagen - Side Effects, Dosage, Interactions - Drugs ...





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