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Actos Drug Description
ACTOS®
(pioglitazone hydrochloride) Tablets

WARNING
CONGESTIVE HEART FAILURE

Thiazolidinediones, including ACTOS, cause or exacerbate congestive heart
failure in some patients (see WARNINGS). After initiation of ACTOS,
and after dose increases, observe patients carefully for signs and symptoms
of heart failure (including excessive, rapid weight gain, dyspnea, and/or
edema). If these signs and symptoms develop, the heart failure should be
managed according to the current standards of care. Furthermore, discontinuation
or dose reduction of ACTOS must be considered.
ACTOS is not recommended in patients with symptomatic heart failure.
Initiation of ACTOS in patients with established NYHA Class III or IV heart
failure is contraindicated (see CONTRAINDICATIONS
and WARNINGS).


DRUG DESCRIPTION



What are the possible side effects of pioglitazone (Actos)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Stop using pioglitazone and call your doctor at once if you have any of these serious side effects:

feeling short of breath, even with mild exertion;
swelling or rapid weight gain;
chest pain, general ill feeling;
nausea, stomach pain, low fever, loss of appetite, dark urine, clay-colored stools,...
Read All Potential Side Effects for Actos »




ACTOS (pioglitazone hydrochloride) is an oral antidiabetic
agent that acts primarily by decreasing insulin resistance. ACTOS is used in
the management of type 2 diabetes mellitus (also known as non-insulin-dependent
diabetes mellitus [NIDDM] or adult-onset diabetes). Pharmacological studies
indicate that ACTOS improves sensitivity to insulin in muscle and adipose
tissue and inhibits hepatic gluconeogenesis. ACTOS improves glycemic control
while reducing circulating insulin levels.
Pioglitazone [(±)-5-[[4-[2-(5-ethyl-2-pyridinyl)ethoxy]phenyl]methyl]-2,4-]
thiazolidinedione monohydrochloride belongs to a different chemical class and
has a different pharmacological action than the sulfonylureas, metformin, or
the α-glucosidase inhibitors. The molecule contains one asymmetric
carbon, and the compound is synthesized and used as the racemic mixture. The
two enantiomers of pioglitazone interconvert in vivo. No differences were
found in the pharmacologic activity between the two enantiomers. The
structural formula is as shown:








Pioglitazone hydrochloride is an odorless white crystalline
powder that has a molecular formula of C19H20N2O3S•HCl
and a molecular weight of 392.90 daltons. It is soluble in N,N-dimethylformamide,
slightly soluble in anhydrous ethanol, very slightly soluble in acetone and
acetonitrile, practically insoluble in water, and insoluble in ether.
ACTOS is available as a tablet for oral administration
containing 15 mg, 30 mg, or 45 mg of pioglitazone (as the base) formulated with
the following excipients: lactose monohydrate NF, hydroxypropylcellulose NF,
carboxymethylcellulose calcium NF, and magnesium stearate NF.Last reviewed on RxList: 9/28/2009




Actos Drug Description
ACTOS®
(pioglitazone hydrochloride) Tablets

WARNING
CONGESTIVE HEART FAILURE

Thiazolidinediones, including ACTOS, cause or exacerbate congestive heart
failure in some patients (see WARNINGS). After initiation of ACTOS,
and after dose increases, observe patients carefully for signs and symptoms
of heart failure (including excessive, rapid weight gain, dyspnea, and/or
edema). If these signs and symptoms develop, the heart failure should be
managed according to the current standards of care. Furthermore, discontinuation
or dose reduction of ACTOS must be considered.
ACTOS is not recommended in patients with symptomatic heart failure.
Initiation of ACTOS in patients with established NYHA Class III or IV heart
failure is contraindicated (see CONTRAINDICATIONS
and WARNINGS).


DRUG DESCRIPTION



What are the possible side effects of pioglitazone (Actos)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Stop using pioglitazone and call your doctor at once if you have any of these serious side effects:

feeling short of breath, even with mild exertion;
swelling or rapid weight gain;
chest pain, general ill feeling;
nausea, stomach pain, low fever, loss of appetite, dark urine, clay-colored stools,...
Read All Potential Side Effects for Actos »




ACTOS (pioglitazone hydrochloride) is an oral antidiabetic
agent that acts primarily by decreasing insulin resistance. ACTOS is used in
the management of type 2 diabetes mellitus (also known as non-insulin-dependent
diabetes mellitus [NIDDM] or adult-onset diabetes). Pharmacological studies
indicate that ACTOS improves sensitivity to insulin in muscle and adipose
tissue and inhibits hepatic gluconeogenesis. ACTOS improves glycemic control
while reducing circulating insulin levels.
Pioglitazone [(±)-5-[[4-[2-(5-ethyl-2-pyridinyl)ethoxy]phenyl]methyl]-2,4-]
thiazolidinedione monohydrochloride belongs to a different chemical class and
has a different pharmacological action than the sulfonylureas, metformin, or
the α-glucosidase inhibitors. The molecule contains one asymmetric
carbon, and the compound is synthesized and used as the racemic mixture. The
two enantiomers of pioglitazone interconvert in vivo. No differences were
found in the pharmacologic activity between the two enantiomers. The
structural formula is as shown:








Pioglitazone hydrochloride is an odorless white crystalline
powder that has a molecular formula of C19H20N2O3S•HCl
and a molecular weight of 392.90 daltons. It is soluble in N,N-dimethylformamide,
slightly soluble in anhydrous ethanol, very slightly soluble in acetone and
acetonitrile, practically insoluble in water, and insoluble in ether.
ACTOS is available as a tablet for oral administration
containing 15 mg, 30 mg, or 45 mg of pioglitazone (as the base) formulated with
the following excipients: lactose monohydrate NF, hydroxypropylcellulose NF,
carboxymethylcellulose calcium NF, and magnesium stearate NF.Last reviewed on RxList: 9/28/2009




Actos Drug Description
ACTOS®
(pioglitazone hydrochloride) Tablets

WARNING
CONGESTIVE HEART FAILURE

Thiazolidinediones, including ACTOS, cause or exacerbate congestive heart
failure in some patients (see WARNINGS). After initiation of ACTOS,
and after dose increases, observe patients carefully for signs and symptoms
of heart failure (including excessive, rapid weight gain, dyspnea, and/or
edema). If these signs and symptoms develop, the heart failure should be
managed according to the current standards of care. Furthermore, discontinuation
or dose reduction of ACTOS must be considered.
ACTOS is not recommended in patients with symptomatic heart failure.
Initiation of ACTOS in patients with established NYHA Class III or IV heart
failure is contraindicated (see CONTRAINDICATIONS
and WARNINGS).


DRUG DESCRIPTION



What are the possible side effects of pioglitazone (Actos)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Stop using pioglitazone and call your doctor at once if you have any of these serious side effects:

feeling short of breath, even with mild exertion;
swelling or rapid weight gain;
chest pain, general ill feeling;
nausea, stomach pain, low fever, loss of appetite, dark urine, clay-colored stools,...
Read All Potential Side Effects for Actos »




ACTOS (pioglitazone hydrochloride) is an oral antidiabetic
agent that acts primarily by decreasing insulin resistance. ACTOS is used in
the management of type 2 diabetes mellitus (also known as non-insulin-dependent
diabetes mellitus [NIDDM] or adult-onset diabetes). Pharmacological studies
indicate that ACTOS improves sensitivity to insulin in muscle and adipose
tissue and inhibits hepatic gluconeogenesis. ACTOS improves glycemic control
while reducing circulating insulin levels.
Pioglitazone [(±)-5-[[4-[2-(5-ethyl-2-pyridinyl)ethoxy]phenyl]methyl]-2,4-]
thiazolidinedione monohydrochloride belongs to a different chemical class and
has a different pharmacological action than the sulfonylureas, metformin, or
the α-glucosidase inhibitors. The molecule contains one asymmetric
carbon, and the compound is synthesized and used as the racemic mixture. The
two enantiomers of pioglitazone interconvert in vivo. No differences were
found in the pharmacologic activity between the two enantiomers. The
structural formula is as shown:








Pioglitazone hydrochloride is an odorless white crystalline
powder that has a molecular formula of C19H20N2O3S•HCl
and a molecular weight of 392.90 daltons. It is soluble in N,N-dimethylformamide,
slightly soluble in anhydrous ethanol, very slightly soluble in acetone and
acetonitrile, practically insoluble in water, and insoluble in ether.
ACTOS is available as a tablet for oral administration
containing 15 mg, 30 mg, or 45 mg of pioglitazone (as the base) formulated with
the following excipients: lactose monohydrate NF, hydroxypropylcellulose NF,
carboxymethylcellulose calcium NF, and magnesium stearate NF.Last reviewed on RxList: 9/28/2009




Actos Drug Description
ACTOS®
(pioglitazone hydrochloride) Tablets

WARNING
CONGESTIVE HEART FAILURE

Thiazolidinediones, including ACTOS, cause or exacerbate congestive heart
failure in some patients (see WARNINGS). After initiation of ACTOS,
and after dose increases, observe patients carefully for signs and symptoms
of heart failure (including excessive, rapid weight gain, dyspnea, and/or
edema). If these signs and symptoms develop, the heart failure should be
managed according to the current standards of care. Furthermore, discontinuation
or dose reduction of ACTOS must be considered.
ACTOS is not recommended in patients with symptomatic heart failure.
Initiation of ACTOS in patients with established NYHA Class III or IV heart
failure is contraindicated (see CONTRAINDICATIONS
and WARNINGS).


DRUG DESCRIPTION



What are the possible side effects of pioglitazone (Actos)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Stop using pioglitazone and call your doctor at once if you have any of these serious side effects:

feeling short of breath, even with mild exertion;
swelling or rapid weight gain;
chest pain, general ill feeling;
nausea, stomach pain, low fever, loss of appetite, dark urine, clay-colored stools,...
Read All Potential Side Effects for Actos »




ACTOS (pioglitazone hydrochloride) is an oral antidiabetic
agent that acts primarily by decreasing insulin resistance. ACTOS is used in
the management of type 2 diabetes mellitus (also known as non-insulin-dependent
diabetes mellitus [NIDDM] or adult-onset diabetes). Pharmacological studies
indicate that ACTOS improves sensitivity to insulin in muscle and adipose
tissue and inhibits hepatic gluconeogenesis. ACTOS improves glycemic control
while reducing circulating insulin levels.
Pioglitazone [(±)-5-[[4-[2-(5-ethyl-2-pyridinyl)ethoxy]phenyl]methyl]-2,4-]
thiazolidinedione monohydrochloride belongs to a different chemical class and
has a different pharmacological action than the sulfonylureas, metformin, or
the α-glucosidase inhibitors. The molecule contains one asymmetric
carbon, and the compound is synthesized and used as the racemic mixture. The
two enantiomers of pioglitazone interconvert in vivo. No differences were
found in the pharmacologic activity between the two enantiomers. The
structural formula is as shown:








Pioglitazone hydrochloride is an odorless white crystalline
powder that has a molecular formula of C19H20N2O3S•HCl
and a molecular weight of 392.90 daltons. It is soluble in N,N-dimethylformamide,
slightly soluble in anhydrous ethanol, very slightly soluble in acetone and
acetonitrile, practically insoluble in water, and insoluble in ether.
ACTOS is available as a tablet for oral administration
containing 15 mg, 30 mg, or 45 mg of pioglitazone (as the base) formulated with
the following excipients: lactose monohydrate NF, hydroxypropylcellulose NF,
carboxymethylcellulose calcium NF, and magnesium stearate NF.Last reviewed on RxList: 9/28/2009




Actos Drug Description
ACTOS®
(pioglitazone hydrochloride) Tablets

WARNING
CONGESTIVE HEART FAILURE

Thiazolidinediones, including ACTOS, cause or exacerbate congestive heart
failure in some patients (see WARNINGS). After initiation of ACTOS,
and after dose increases, observe patients carefully for signs and symptoms
of heart failure (including excessive, rapid weight gain, dyspnea, and/or
edema). If these signs and symptoms develop, the heart failure should be
managed according to the current standards of care. Furthermore, discontinuation
or dose reduction of ACTOS must be considered.
ACTOS is not recommended in patients with symptomatic heart failure.
Initiation of ACTOS in patients with established NYHA Class III or IV heart
failure is contraindicated (see CONTRAINDICATIONS
and WARNINGS).


DRUG DESCRIPTION



What are the possible side effects of pioglitazone (Actos)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Stop using pioglitazone and call your doctor at once if you have any of these serious side effects:

feeling short of breath, even with mild exertion;
swelling or rapid weight gain;
chest pain, general ill feeling;
nausea, stomach pain, low fever, loss of appetite, dark urine, clay-colored stools,...
Read All Potential Side Effects for Actos »




ACTOS (pioglitazone hydrochloride) is an oral antidiabetic
agent that acts primarily by decreasing insulin resistance. ACTOS is used in
the management of type 2 diabetes mellitus (also known as non-insulin-dependent
diabetes mellitus [NIDDM] or adult-onset diabetes). Pharmacological studies
indicate that ACTOS improves sensitivity to insulin in muscle and adipose
tissue and inhibits hepatic gluconeogenesis. ACTOS improves glycemic control
while reducing circulating insulin levels.
Pioglitazone [(±)-5-[[4-[2-(5-ethyl-2-pyridinyl)ethoxy]phenyl]methyl]-2,4-]
thiazolidinedione monohydrochloride belongs to a different chemical class and
has a different pharmacological action than the sulfonylureas, metformin, or
the α-glucosidase inhibitors. The molecule contains one asymmetric
carbon, and the compound is synthesized and used as the racemic mixture. The
two enantiomers of pioglitazone interconvert in vivo. No differences were
found in the pharmacologic activity between the two enantiomers. The
structural formula is as shown:








Pioglitazone hydrochloride is an odorless white crystalline
powder that has a molecular formula of C19H20N2O3S•HCl
and a molecular weight of 392.90 daltons. It is soluble in N,N-dimethylformamide,
slightly soluble in anhydrous ethanol, very slightly soluble in acetone and
acetonitrile, practically insoluble in water, and insoluble in ether.
ACTOS is available as a tablet for oral administration
containing 15 mg, 30 mg, or 45 mg of pioglitazone (as the base) formulated with
the following excipients: lactose monohydrate NF, hydroxypropylcellulose NF,
carboxymethylcellulose calcium NF, and magnesium stearate NF.Last reviewed on RxList: 9/28/2009





Other reviews about Actos on wordpress

Updated Labelling For Diabetes Drug Actos And Risk Of Heart Failure, Canada
  by healtherm2
Health Canada is informing diabetic patients taking Actos (the brand name for the prescription drug pioglitazone hydrochloride) of recent changes to the prescribing information for this product. […]


Avandia Raises Heart Failure Risk More Than Actos
  by timeinctemp
TUESDAY, Aug. 18 (HealthDay News) — The type 2 diabetes drug Avandia (rosiglitazone) increases the risk of heart failure and death more than another drug in the same […]


Takeda Canada's Opening Move: Reacquire Rights to Diabetes Drug ACTOS from Eli Lilly Canada
  by Jeremy G
Takeda Canada, which opened in Mississauga in March, bought back the commercial rights to pioglitazone HCl, a type 2 diabetes drug marketed as ACTOS, from Eli Lilly Canada. […]


Diabetes Drugs Avandia, Actos Tied to Fractures in Women
  by timeinctemp
MONDAY, Feb. 15 (HealthDay News) — Women who take diabetes drugs known as thiazolidinediones, which include Avandia and Actos, are at a greater risk of bone fractures, a […]


Diabetes: Avandia Drug Trial Unethical And Dangerous
  by Roger Alexander
The Canadian physician whose research escalated safety concerns about the Type 2 diabetes drug rosiglitazone (marketed as Avandia) is urging the US Food and Drug Administrationto call a […]


Actos Helps In Treatment of Diabetes
  by TotalDrugmart.com
ACTOS is a once-daily oral prescription medication that, with diet and exercise, has been shown to be effective for the treatment of type 2 diabetes.  ACTOS […]


Actos, Takeda's Diabetes Drug has Same Heart Risks as Avandia
  by jeffreynewmanlaw
Actos, a major selling diabetes drug causes major heart problems just as Avandia, the drug recently reviewed by the FDA and required to increase warnings. Sales of Avandia […]


Diabetes Alert: Actos Linked To Bladder Cancer
  by Roger Alexander
After Avandia, it is now the turn of Actos to be linked to life-threatening conditions. On September 17 the United States Food and Drug Administration […]


FDA Reviewing Safety Information on Actos (Pioglitazone)
  by Marvin Pankaskie
The U.S. Food and Drug Administration today announced it has begun a safety review of the diabetes drug Actos (pioglitazone), after receiving preliminary results from a […]


FDA MedWatch - Actos (pioglitazone): Ongoing Safety Review - Potential Increased Risk of Bladder Cancer
  by irbtipoftheweek
ISSUE: FDA notified healthcare professionals and patients that the Agency is reviewing data from an ongoing, ten-year epidemiological study designed to evaluate whether Actos (pioglitazone) is associated with […]



Other reviews about Actos on web:

ACTOS is a prescription medication used with diet and exercise to improve blood sugar (glucose) control in adults with type 2 diabetes. ACTOS is not for patients with type 1 ... ACTOS, A Type 2 Diabetes Treatment


Actos (pioglitazone) is an oral diabetes medicine used to treat type 2 (non-insulin-dependent) diabetes. Includes Actos side effects, interactions and indications. Actos Information from Drugs.com


Learn about the prescription medication Actos (Pioglitazone Hydrochloride), drug uses, dosage, side effects, drug interactions, warnings, reviews and patient labeling. Actos (Pioglitazone Hydrochloride) Drug Information: Uses, Side ...


ACTOS is a prescription medication used with diet and exercise to improve blood sugar (glucose) control in adults with type 2 diabetes. ACTOS is not for patients with type 1 ... A Once-daily Oral Medication For Type 2 Diabetes: ACTOS


Accurate, FDA approved Actos information for healthcare professionals and patients - brought to you by Drugs.com. Actos Official FDA information, side effects and uses.


Pioglitazone is a prescription drug of the class thiazolidinedione (TZD) with hypoglycemic (antihyperglycemic, antidiabetic) action. Pioglitazone is marketed as trademarks Actos in the ... Pioglitazone - Wikipedia, the free encyclopedia


Find patient medical information for Actos Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. Actos Oral : Uses, Side Effects, Interactions, Pictures, Warnings ...


Lawyer representing Actos diabetic drug users who have developed congestive heart failure including Primary Pulmonary Hypertension PPH and heart failure. Free Actos heart ... Actos Side Effects | Heart Disease Heart Failure Lawyer Attorney ...


–noun, plural-tos /-toʊz; Sp.-tɔs / Show Spelled [-tohz; Sp.-taws] Show IPA. Southwestern U.S. a short, realistic play, usually in spanish, that dramatizes the social and ... Actos | Define Actos at Dictionary.com


Learn more about Actos. Find the Web's best health guides, medical reports, news, videos and tools for Actos. Share Actos experiences and get advice from experts. Actos Overview - References, Advice, News, Videos, Coping & Support





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