Reviews Abraxane


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Abraxane Drug Description
ABRAXANE® for Injectable Suspension
(paclitaxel protein-bound particles) for Injectable
Suspension
(albumin-bound)

WARNING
ABRAXANE for Injectable Suspension (paclitaxel
protein-bound particles for injectable suspension) should be administered under
the supervision of a physician experienced in the use of cancer
chemotherapeutic agents. Appropriate management of complications is possible
only when adequate diagnostic and treatment facilities are readily available.
ABRAXANE therapy should not be administered to patients
with metastatic breast cancer who have baseline neutrophil counts of less than
1,500 cells/mm³. In order to monitor the occurrence of bone marrow suppression,
primarily neutropenia, which may be severe and result in infection, it is
recommended that frequent peripheral blood cell counts be performed on all
patients receiving ABRAXANE.
Note: An albumin form of paclitaxel may substantially
affect a drug's functional properties relative to those of drug in solution. DO
NOT SUBSTITUTE FOR OR WITH OTHER PACLITAXEL FORMULATIONS.

DRUG DESCRIPTION



What are the possible side effects of paclitaxel protein-bound (Abraxane)?

If you experience any of the following serious side effects from paclitaxel protein-bound, seek emergency medical attention or contact your doctor immediately:

an allergic reaction (including difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives);
decreased bone marrow function and blood problems (extreme fatigue; easy bruising or bleeding; black, bloody or tarry stools; fever or chills; or signs of infection);
liver damage...
Read All Potential Side Effects for Abraxane »




ABRAXANE for Injectable Suspension (paclitaxel protein-bound
particles for injectable suspension) is an albumin-bound form of paclitaxel
with a mean particle size of approximately 130 nanometers. Paclitaxel exists in
the particles in a non-crystalline, amorphous state. ABRAXANE is supplied as a
white to yellow, sterile, lyophilized powder for reconstitution with 20 mL of
0.9% Sodium Chloride Injection, USP prior to intravenous infusion. Each
single-use vial contains 100 mg of paclitaxel and approximately 900 mg of human
albumin. Each milliliter (mL) of reconstituted suspension contains 5 mg
paclitaxel. ABRAXANE is free of solvents.
The active agent in ABRAXANE® is paclitaxel, a natural
product with antitumor activity. Paclitaxel is obtained from Taxus media.
The chemical name for paclitaxel is 5β,20-Epoxy-1,2α,4,7β,10β,13αhexahydroxytax-11-en-9-one
4,10-diacetate 2-benzoate 13-ester with (2R,3S)-N-benzoyl-3phenylisoserine.
Paclitaxel has the following structural formula:








Paclitaxel is a white to off-white crystalline powder with
the empirical formula C47H51NO14 and a
molecular weight of 853.91. It is highly lipophilic, insoluble in water, and
melts at approximately 216°C to 217°C.Last reviewed on RxList: 7/8/2009




Abraxane Drug Description
ABRAXANE® for Injectable Suspension
(paclitaxel protein-bound particles) for Injectable
Suspension
(albumin-bound)

WARNING
ABRAXANE for Injectable Suspension (paclitaxel
protein-bound particles for injectable suspension) should be administered under
the supervision of a physician experienced in the use of cancer
chemotherapeutic agents. Appropriate management of complications is possible
only when adequate diagnostic and treatment facilities are readily available.
ABRAXANE therapy should not be administered to patients
with metastatic breast cancer who have baseline neutrophil counts of less than
1,500 cells/mm³. In order to monitor the occurrence of bone marrow suppression,
primarily neutropenia, which may be severe and result in infection, it is
recommended that frequent peripheral blood cell counts be performed on all
patients receiving ABRAXANE.
Note: An albumin form of paclitaxel may substantially
affect a drug's functional properties relative to those of drug in solution. DO
NOT SUBSTITUTE FOR OR WITH OTHER PACLITAXEL FORMULATIONS.

DRUG DESCRIPTION



What are the possible side effects of paclitaxel protein-bound (Abraxane)?

If you experience any of the following serious side effects from paclitaxel protein-bound, seek emergency medical attention or contact your doctor immediately:

an allergic reaction (including difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives);
decreased bone marrow function and blood problems (extreme fatigue; easy bruising or bleeding; black, bloody or tarry stools; fever or chills; or signs of infection);
liver damage...
Read All Potential Side Effects for Abraxane »




ABRAXANE for Injectable Suspension (paclitaxel protein-bound
particles for injectable suspension) is an albumin-bound form of paclitaxel
with a mean particle size of approximately 130 nanometers. Paclitaxel exists in
the particles in a non-crystalline, amorphous state. ABRAXANE is supplied as a
white to yellow, sterile, lyophilized powder for reconstitution with 20 mL of
0.9% Sodium Chloride Injection, USP prior to intravenous infusion. Each
single-use vial contains 100 mg of paclitaxel and approximately 900 mg of human
albumin. Each milliliter (mL) of reconstituted suspension contains 5 mg
paclitaxel. ABRAXANE is free of solvents.
The active agent in ABRAXANE® is paclitaxel, a natural
product with antitumor activity. Paclitaxel is obtained from Taxus media.
The chemical name for paclitaxel is 5β,20-Epoxy-1,2α,4,7β,10β,13αhexahydroxytax-11-en-9-one
4,10-diacetate 2-benzoate 13-ester with (2R,3S)-N-benzoyl-3phenylisoserine.
Paclitaxel has the following structural formula:








Paclitaxel is a white to off-white crystalline powder with
the empirical formula C47H51NO14 and a
molecular weight of 853.91. It is highly lipophilic, insoluble in water, and
melts at approximately 216°C to 217°C.Last reviewed on RxList: 7/8/2009




Abraxane Drug Description
ABRAXANE® for Injectable Suspension
(paclitaxel protein-bound particles) for Injectable
Suspension
(albumin-bound)

WARNING
ABRAXANE for Injectable Suspension (paclitaxel
protein-bound particles for injectable suspension) should be administered under
the supervision of a physician experienced in the use of cancer
chemotherapeutic agents. Appropriate management of complications is possible
only when adequate diagnostic and treatment facilities are readily available.
ABRAXANE therapy should not be administered to patients
with metastatic breast cancer who have baseline neutrophil counts of less than
1,500 cells/mm³. In order to monitor the occurrence of bone marrow suppression,
primarily neutropenia, which may be severe and result in infection, it is
recommended that frequent peripheral blood cell counts be performed on all
patients receiving ABRAXANE.
Note: An albumin form of paclitaxel may substantially
affect a drug's functional properties relative to those of drug in solution. DO
NOT SUBSTITUTE FOR OR WITH OTHER PACLITAXEL FORMULATIONS.

DRUG DESCRIPTION



What are the possible side effects of paclitaxel protein-bound (Abraxane)?

If you experience any of the following serious side effects from paclitaxel protein-bound, seek emergency medical attention or contact your doctor immediately:

an allergic reaction (including difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives);
decreased bone marrow function and blood problems (extreme fatigue; easy bruising or bleeding; black, bloody or tarry stools; fever or chills; or signs of infection);
liver damage...
Read All Potential Side Effects for Abraxane »




ABRAXANE for Injectable Suspension (paclitaxel protein-bound
particles for injectable suspension) is an albumin-bound form of paclitaxel
with a mean particle size of approximately 130 nanometers. Paclitaxel exists in
the particles in a non-crystalline, amorphous state. ABRAXANE is supplied as a
white to yellow, sterile, lyophilized powder for reconstitution with 20 mL of
0.9% Sodium Chloride Injection, USP prior to intravenous infusion. Each
single-use vial contains 100 mg of paclitaxel and approximately 900 mg of human
albumin. Each milliliter (mL) of reconstituted suspension contains 5 mg
paclitaxel. ABRAXANE is free of solvents.
The active agent in ABRAXANE® is paclitaxel, a natural
product with antitumor activity. Paclitaxel is obtained from Taxus media.
The chemical name for paclitaxel is 5β,20-Epoxy-1,2α,4,7β,10β,13αhexahydroxytax-11-en-9-one
4,10-diacetate 2-benzoate 13-ester with (2R,3S)-N-benzoyl-3phenylisoserine.
Paclitaxel has the following structural formula:








Paclitaxel is a white to off-white crystalline powder with
the empirical formula C47H51NO14 and a
molecular weight of 853.91. It is highly lipophilic, insoluble in water, and
melts at approximately 216°C to 217°C.Last reviewed on RxList: 7/8/2009




Abraxane Drug Description
ABRAXANE® for Injectable Suspension
(paclitaxel protein-bound particles) for Injectable
Suspension
(albumin-bound)

WARNING
ABRAXANE for Injectable Suspension (paclitaxel
protein-bound particles for injectable suspension) should be administered under
the supervision of a physician experienced in the use of cancer
chemotherapeutic agents. Appropriate management of complications is possible
only when adequate diagnostic and treatment facilities are readily available.
ABRAXANE therapy should not be administered to patients
with metastatic breast cancer who have baseline neutrophil counts of less than
1,500 cells/mm³. In order to monitor the occurrence of bone marrow suppression,
primarily neutropenia, which may be severe and result in infection, it is
recommended that frequent peripheral blood cell counts be performed on all
patients receiving ABRAXANE.
Note: An albumin form of paclitaxel may substantially
affect a drug's functional properties relative to those of drug in solution. DO
NOT SUBSTITUTE FOR OR WITH OTHER PACLITAXEL FORMULATIONS.

DRUG DESCRIPTION



What are the possible side effects of paclitaxel protein-bound (Abraxane)?

If you experience any of the following serious side effects from paclitaxel protein-bound, seek emergency medical attention or contact your doctor immediately:

an allergic reaction (including difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives);
decreased bone marrow function and blood problems (extreme fatigue; easy bruising or bleeding; black, bloody or tarry stools; fever or chills; or signs of infection);
liver damage...
Read All Potential Side Effects for Abraxane »




ABRAXANE for Injectable Suspension (paclitaxel protein-bound
particles for injectable suspension) is an albumin-bound form of paclitaxel
with a mean particle size of approximately 130 nanometers. Paclitaxel exists in
the particles in a non-crystalline, amorphous state. ABRAXANE is supplied as a
white to yellow, sterile, lyophilized powder for reconstitution with 20 mL of
0.9% Sodium Chloride Injection, USP prior to intravenous infusion. Each
single-use vial contains 100 mg of paclitaxel and approximately 900 mg of human
albumin. Each milliliter (mL) of reconstituted suspension contains 5 mg
paclitaxel. ABRAXANE is free of solvents.
The active agent in ABRAXANE® is paclitaxel, a natural
product with antitumor activity. Paclitaxel is obtained from Taxus media.
The chemical name for paclitaxel is 5β,20-Epoxy-1,2α,4,7β,10β,13αhexahydroxytax-11-en-9-one
4,10-diacetate 2-benzoate 13-ester with (2R,3S)-N-benzoyl-3phenylisoserine.
Paclitaxel has the following structural formula:








Paclitaxel is a white to off-white crystalline powder with
the empirical formula C47H51NO14 and a
molecular weight of 853.91. It is highly lipophilic, insoluble in water, and
melts at approximately 216°C to 217°C.Last reviewed on RxList: 7/8/2009




Abraxane Drug Description
ABRAXANE® for Injectable Suspension
(paclitaxel protein-bound particles) for Injectable
Suspension
(albumin-bound)

WARNING
ABRAXANE for Injectable Suspension (paclitaxel
protein-bound particles for injectable suspension) should be administered under
the supervision of a physician experienced in the use of cancer
chemotherapeutic agents. Appropriate management of complications is possible
only when adequate diagnostic and treatment facilities are readily available.
ABRAXANE therapy should not be administered to patients
with metastatic breast cancer who have baseline neutrophil counts of less than
1,500 cells/mm³. In order to monitor the occurrence of bone marrow suppression,
primarily neutropenia, which may be severe and result in infection, it is
recommended that frequent peripheral blood cell counts be performed on all
patients receiving ABRAXANE.
Note: An albumin form of paclitaxel may substantially
affect a drug's functional properties relative to those of drug in solution. DO
NOT SUBSTITUTE FOR OR WITH OTHER PACLITAXEL FORMULATIONS.

DRUG DESCRIPTION



What are the possible side effects of paclitaxel protein-bound (Abraxane)?

If you experience any of the following serious side effects from paclitaxel protein-bound, seek emergency medical attention or contact your doctor immediately:

an allergic reaction (including difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives);
decreased bone marrow function and blood problems (extreme fatigue; easy bruising or bleeding; black, bloody or tarry stools; fever or chills; or signs of infection);
liver damage...
Read All Potential Side Effects for Abraxane »




ABRAXANE for Injectable Suspension (paclitaxel protein-bound
particles for injectable suspension) is an albumin-bound form of paclitaxel
with a mean particle size of approximately 130 nanometers. Paclitaxel exists in
the particles in a non-crystalline, amorphous state. ABRAXANE is supplied as a
white to yellow, sterile, lyophilized powder for reconstitution with 20 mL of
0.9% Sodium Chloride Injection, USP prior to intravenous infusion. Each
single-use vial contains 100 mg of paclitaxel and approximately 900 mg of human
albumin. Each milliliter (mL) of reconstituted suspension contains 5 mg
paclitaxel. ABRAXANE is free of solvents.
The active agent in ABRAXANE® is paclitaxel, a natural
product with antitumor activity. Paclitaxel is obtained from Taxus media.
The chemical name for paclitaxel is 5β,20-Epoxy-1,2α,4,7β,10β,13αhexahydroxytax-11-en-9-one
4,10-diacetate 2-benzoate 13-ester with (2R,3S)-N-benzoyl-3phenylisoserine.
Paclitaxel has the following structural formula:








Paclitaxel is a white to off-white crystalline powder with
the empirical formula C47H51NO14 and a
molecular weight of 853.91. It is highly lipophilic, insoluble in water, and
melts at approximately 216°C to 217°C.Last reviewed on RxList: 7/8/2009





Other reviews about Abraxane on wordpress

Abraxane
  by 3102sly
NY Times October 1, 2006 Hope, at $4,200 a Dose Facts: Abraxane costs $4,200 a dose, nearly 25 times as much as its closest competitor Taxol. It is a […]


nab-Paclitaxel (Abraxane) and sorafenib (Nexavar) for First-Line Treatment of Metastatic Breast Cancer
  by bmirtsching
Barry C. Mirtsching, MD at CORT is the lead investigator for the International Oncology Network (ION) trial of Abraxane and sorafenib (Nexavar) for first-line treatment of metastatic breast […]


Abraxane (nab-paclitaxel) with or without Herceptin in First-Line Treatment of Metastatic Breast Cancer: ION 04-012 Study Results from the ASCO 2008 Annual Meeting
  by bmirtsching
The International Oncology Network (ION) Study 04-012 results were presented in a poster presentation at the ASCO 2008 Annual Meeting.  This study was an open label Phase II […]


Abraxis BioScience Launches Abraxane(R) In European Union
  by yestelli
Abraxis BioScience, Inc. (NASDAQ:ABII), a fully integrated, global biotechnology company, announced the launch in the European Union of Abraxane® Paclitaxel 5 mg/ml powder for suspension for infusion. Abraxane® […]


Northwest Biotherapeutics Reports Encouraging Data On First Patients Who Have Completed Its Phase I/II Clinical Trial Of DCVax(R)-L In Ovarian Cancer
  by yestelli
(OTC Bulletin Board: NWBO; AIM: NWBT and NWBS) Northwest Biotherapeutics, Inc. ("NWBT") announced encouraging data on clinical responses in the first two case reports of patients who have […]


Chemo verdict: Abraxane + Gemzar
  by pinehouse
I was so glad that I got a hold of the PET/CT report yesterday, the day before my appointment with the oncologist.  I was so glad that I […]


First cycle of Abraxane+Gemzar
  by pinehouse
After having a grand time earlier this week with a couple of good friends (one with her lovely daughter), now it's payback time.  I still have to go […]


Nanoparticles in clinical trial trends : comments & focus on Abraxane
  by nanocolors
There are currently 70 clinical trials mentionning "nanoparticles" registered in the Clinicaltrials.gov database.  As shown in the dedicated Nanocolors trend chart dashboard, these are mostly Phase I and Phase II […]


Drug May Extend Life When Breast Cancer Spreads
  by timeinctemp
TUESDAY, May 26 (HealthDay News) — A new study affirms that the chemotherapy drug Abraxane is more effective, with less troublesome side effects, than the current drug of […]


A generic version of Abraxane withdrawn from the Indian market
  by nanocolors
Albupax was initially launched on the Indian market in September 2008 by Natco Pharma, an Indian pharmaceutical company.  Albupax is a generic version of the nanotechnology-based Abraxane drug by […]



Other reviews about Abraxane on web:

ABRAXANE is a breast cancer treatment drug that does not contain chemical solvents, and is administered in just 30 minutes. Metastatic Breast Cancer Treatment Drug - ABRAXANE


Accurate, FDA approved Abraxane information for healthcare professionals and patients - brought to you by Drugs.com. Abraxane Official FDA information, side effects and uses.


Learn about the prescription medication Abraxane (Albumin-bound Paclitaxel), drug uses, dosage, side effects, drug interactions, warnings, reviews and patient labeling. Abraxane (Albumin-bound Paclitaxel) Drug Information: Uses, Side ...


Abraxane (paclitaxel) is an antineoplastic medication used in the treatment breast cancer. Includes Abraxane side effects, interactions and indications. Abraxane Information from Drugs.com


Abraxane is a chemotherapy drug used to treat breast cancer after failure of combination chemotherapy. Another name for chemo drug Abraxane is Paclitaxel Protein-bound. Learn more ... Abraxane, Paclitaxel Protein-Bound - Chemotherapy Drugs, Chemo ...


Side effects of ABRAXANE, a Metastatic Breast Cancer Treatment Drug. Metastatic Breast Cancer Treatment Drug Side Effects - ABRAXANE


It is sold in the United States under the trade name Abraxane by Abraxis Bioscience. This treatment was approved by the Food and Drug Administration in January 2005 for breast cancer ... Protein-bound paclitaxel - Wikipedia, the free encyclopedia


Available by prescription, Abraxane is a drug that is used for treating breast cancer. This part of the eMedTV archives explains how Abraxane works and offers more details on its ... Abraxane


Abraxane is a unique formulation of nanoparticle albumin-bound (NAB)paclitaxel. It was developed to overcome solubility issues that existed ... Abraxane: 46 user reviews - DailyStrength


Find patient medical information for Abraxane IV on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. Abraxane IV : Uses, Side Effects, Interactions, Pictures, Warnings ...





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