Reviews 20% I.V. Fat Emulsion


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Intralipid 20% Drug Description
Intralipid® 20%
(20% I.V. Fat Emulsion)
In Excel® Container
DRUG DESCRIPTION
INTRALIPID® 20% (A 20% INTRAVENOUS FAT EMULSION) IS A STERILE, NON-PYROGENIC
FAT EMULSION PREPARED FOR INTRAVENOUS ADMINISTRATION AS A SOURCE OF CALORIES
AND ESSENTIAL FATTY ACIDS. IT IS MADE UP OF 20% SOYBEAN OIL, 1.2% EGG YOLK PHOSPHOLIPIDS,
2.25% GLYCERIN, AND WATER FOR INJECTION. IN ADDITION, SODIUM HYDROXIDE HAS BEEN
ADDED TO ADJUST THE PH SO THAT THE FINAL PRODUCT PH IS 8. PH RANGE IS 6 TO 8.9.
The soybean oil is a refined natural product consisting of a mixture of neutral
triglycerides of predominantly unsaturated fatty acids with the following structure:







- ARE SATURATED AND UNSATURATED FATTY ACID RESIDUES.
The major component fatty acids are linoleic (44-62%), oleic (19-30%), palmitic
(7-14%), linolenic (4-11%) and stearic (1.4-5.5%)1. These fatty acids
have the following chemical and structural formulas:









PURIFIED EGG PHOSPHATIDES ARE A MIXTURE OF NATURALLY OCCURRING PHOSPHOLIPIDS
WHICH ARE ISOLATED FROM THE EGG YOLK. THESE PHOSPHOLIPIDS HAVE THE FOLLOWING
GENERAL STRUCTURE:









R1C- AND R2C- CONTAIN SATURATED AND UNSATURATED FATTY
ACIDS THAT ABOUND IN NEUTRAL FATS. R3 IS PRIMARILY EITHER THE CHOLINE
OR ETHANOLAMINE ESTER OF PHOSPHORIC ACID.







GLYCERIN IS CHEMICALLY DESIGNATED C3H8O3 AND IS A CLEAR COLORLESS, HYGROSCOPIC
SYRUPY LIQUID. IT HAS THE FOLLOWING STRUCTURAL FORMULA:







INTRALIPID® 20% (A 20% INTRAVENOUSA FAT EMULSION) HAS AN OSMOLALITY OF
APPROXIMATELY 350 MOSMOL/KG WATER (WHICH REPRESENTS 260 MOSMOL/LITER OF EMULSION)
AND CONTAINS EMULSIFIED FAT PARTICLES OF APPROXIMATELY 0.5 MICRON SIZE.
THE TOTAL CALORIC VALUE, INCLUDING FAT, PHOSPHOLIPID AND GLYCERIN, IS 2.0 KCAL
PER ML OF INTRALIPID® 20%. THE PHOSPHOLIPIDS PRESENT CONTRIBUTE 47 MILLIGRAMS
OR APPROXIMATELY 1.5 MMOL OF PHOSPHORUS PER 100 ML OF THE EMULSION.
THE PRIMARY CONTAINER IS MANUFACTURED FROM EXCEL® FILM, A POLYPROPYLENE
BASED MATERIAL COMPRISED OF THREE CO-EXTRUDED LAYERS.
THE PLASTIC CONTAINER IS MADE FROM MULTILAYERED FILM SPECIFICALLY DESIGNED
FOR PARENTERAL DRUGS. IT CONTAINS NO PLASTICIZERS AND EXHIBITS VIRTUALLY NO
LEACHABLES. THE SOLUTION CONTACT LAYER IS A RUBBERIZED COPOLYMER OF ETHYLENE
AND PROPYLENE. THE CONTAINER IS NONTOXIC AND BIOLOGICALLY INERT. THE CONTAINER-SOLUTION
UNIT IS A CLOSED SYSTEM AND IS NOT DEPENDENT UPON ENTRY OF EXTERNAL AIR DURING
ADMINISTRATION. THE CONTAINER IS OVERWRAPPED TO PROVIDE PROTECTION FROM THE
PHYSICAL ENVIRONMENT AND TO PROVIDE AN ADDITIONAL MOISTURE BARRIER WHEN NECESSARY.
1. PADLEY FB: "MAJOR VEGETABLE FATS," THE LIPID
HANDBOOK (GUNSTONE FD, HARWOOD JL, PADLEY FB, EDS.), CHAPMAN AND HALL LTD.,
CAMBRIDGE, UK (1986), PP. 88-9.Last reviewed on RxList: 7/30/2007




Intralipid 20% Drug Description
Intralipid® 20%
(20% I.V. Fat Emulsion)
In Excel® Container
DRUG DESCRIPTION
INTRALIPID® 20% (A 20% INTRAVENOUS FAT EMULSION) IS A STERILE, NON-PYROGENIC
FAT EMULSION PREPARED FOR INTRAVENOUS ADMINISTRATION AS A SOURCE OF CALORIES
AND ESSENTIAL FATTY ACIDS. IT IS MADE UP OF 20% SOYBEAN OIL, 1.2% EGG YOLK PHOSPHOLIPIDS,
2.25% GLYCERIN, AND WATER FOR INJECTION. IN ADDITION, SODIUM HYDROXIDE HAS BEEN
ADDED TO ADJUST THE PH SO THAT THE FINAL PRODUCT PH IS 8. PH RANGE IS 6 TO 8.9.
The soybean oil is a refined natural product consisting of a mixture of neutral
triglycerides of predominantly unsaturated fatty acids with the following structure:







- ARE SATURATED AND UNSATURATED FATTY ACID RESIDUES.
The major component fatty acids are linoleic (44-62%), oleic (19-30%), palmitic
(7-14%), linolenic (4-11%) and stearic (1.4-5.5%)1. These fatty acids
have the following chemical and structural formulas:









PURIFIED EGG PHOSPHATIDES ARE A MIXTURE OF NATURALLY OCCURRING PHOSPHOLIPIDS
WHICH ARE ISOLATED FROM THE EGG YOLK. THESE PHOSPHOLIPIDS HAVE THE FOLLOWING
GENERAL STRUCTURE:









R1C- AND R2C- CONTAIN SATURATED AND UNSATURATED FATTY
ACIDS THAT ABOUND IN NEUTRAL FATS. R3 IS PRIMARILY EITHER THE CHOLINE
OR ETHANOLAMINE ESTER OF PHOSPHORIC ACID.







GLYCERIN IS CHEMICALLY DESIGNATED C3H8O3 AND IS A CLEAR COLORLESS, HYGROSCOPIC
SYRUPY LIQUID. IT HAS THE FOLLOWING STRUCTURAL FORMULA:







INTRALIPID® 20% (A 20% INTRAVENOUSA FAT EMULSION) HAS AN OSMOLALITY OF
APPROXIMATELY 350 MOSMOL/KG WATER (WHICH REPRESENTS 260 MOSMOL/LITER OF EMULSION)
AND CONTAINS EMULSIFIED FAT PARTICLES OF APPROXIMATELY 0.5 MICRON SIZE.
THE TOTAL CALORIC VALUE, INCLUDING FAT, PHOSPHOLIPID AND GLYCERIN, IS 2.0 KCAL
PER ML OF INTRALIPID® 20%. THE PHOSPHOLIPIDS PRESENT CONTRIBUTE 47 MILLIGRAMS
OR APPROXIMATELY 1.5 MMOL OF PHOSPHORUS PER 100 ML OF THE EMULSION.
THE PRIMARY CONTAINER IS MANUFACTURED FROM EXCEL® FILM, A POLYPROPYLENE
BASED MATERIAL COMPRISED OF THREE CO-EXTRUDED LAYERS.
THE PLASTIC CONTAINER IS MADE FROM MULTILAYERED FILM SPECIFICALLY DESIGNED
FOR PARENTERAL DRUGS. IT CONTAINS NO PLASTICIZERS AND EXHIBITS VIRTUALLY NO
LEACHABLES. THE SOLUTION CONTACT LAYER IS A RUBBERIZED COPOLYMER OF ETHYLENE
AND PROPYLENE. THE CONTAINER IS NONTOXIC AND BIOLOGICALLY INERT. THE CONTAINER-SOLUTION
UNIT IS A CLOSED SYSTEM AND IS NOT DEPENDENT UPON ENTRY OF EXTERNAL AIR DURING
ADMINISTRATION. THE CONTAINER IS OVERWRAPPED TO PROVIDE PROTECTION FROM THE
PHYSICAL ENVIRONMENT AND TO PROVIDE AN ADDITIONAL MOISTURE BARRIER WHEN NECESSARY.
1. PADLEY FB: "MAJOR VEGETABLE FATS," THE LIPID
HANDBOOK (GUNSTONE FD, HARWOOD JL, PADLEY FB, EDS.), CHAPMAN AND HALL LTD.,
CAMBRIDGE, UK (1986), PP. 88-9.Last reviewed on RxList: 7/30/2007




Intralipid 20% Drug Description
Intralipid® 20%
(20% I.V. Fat Emulsion)
In Excel® Container
DRUG DESCRIPTION
INTRALIPID® 20% (A 20% INTRAVENOUS FAT EMULSION) IS A STERILE, NON-PYROGENIC
FAT EMULSION PREPARED FOR INTRAVENOUS ADMINISTRATION AS A SOURCE OF CALORIES
AND ESSENTIAL FATTY ACIDS. IT IS MADE UP OF 20% SOYBEAN OIL, 1.2% EGG YOLK PHOSPHOLIPIDS,
2.25% GLYCERIN, AND WATER FOR INJECTION. IN ADDITION, SODIUM HYDROXIDE HAS BEEN
ADDED TO ADJUST THE PH SO THAT THE FINAL PRODUCT PH IS 8. PH RANGE IS 6 TO 8.9.
The soybean oil is a refined natural product consisting of a mixture of neutral
triglycerides of predominantly unsaturated fatty acids with the following structure:







- ARE SATURATED AND UNSATURATED FATTY ACID RESIDUES.
The major component fatty acids are linoleic (44-62%), oleic (19-30%), palmitic
(7-14%), linolenic (4-11%) and stearic (1.4-5.5%)1. These fatty acids
have the following chemical and structural formulas:









PURIFIED EGG PHOSPHATIDES ARE A MIXTURE OF NATURALLY OCCURRING PHOSPHOLIPIDS
WHICH ARE ISOLATED FROM THE EGG YOLK. THESE PHOSPHOLIPIDS HAVE THE FOLLOWING
GENERAL STRUCTURE:









R1C- AND R2C- CONTAIN SATURATED AND UNSATURATED FATTY
ACIDS THAT ABOUND IN NEUTRAL FATS. R3 IS PRIMARILY EITHER THE CHOLINE
OR ETHANOLAMINE ESTER OF PHOSPHORIC ACID.







GLYCERIN IS CHEMICALLY DESIGNATED C3H8O3 AND IS A CLEAR COLORLESS, HYGROSCOPIC
SYRUPY LIQUID. IT HAS THE FOLLOWING STRUCTURAL FORMULA:







INTRALIPID® 20% (A 20% INTRAVENOUSA FAT EMULSION) HAS AN OSMOLALITY OF
APPROXIMATELY 350 MOSMOL/KG WATER (WHICH REPRESENTS 260 MOSMOL/LITER OF EMULSION)
AND CONTAINS EMULSIFIED FAT PARTICLES OF APPROXIMATELY 0.5 MICRON SIZE.
THE TOTAL CALORIC VALUE, INCLUDING FAT, PHOSPHOLIPID AND GLYCERIN, IS 2.0 KCAL
PER ML OF INTRALIPID® 20%. THE PHOSPHOLIPIDS PRESENT CONTRIBUTE 47 MILLIGRAMS
OR APPROXIMATELY 1.5 MMOL OF PHOSPHORUS PER 100 ML OF THE EMULSION.
THE PRIMARY CONTAINER IS MANUFACTURED FROM EXCEL® FILM, A POLYPROPYLENE
BASED MATERIAL COMPRISED OF THREE CO-EXTRUDED LAYERS.
THE PLASTIC CONTAINER IS MADE FROM MULTILAYERED FILM SPECIFICALLY DESIGNED
FOR PARENTERAL DRUGS. IT CONTAINS NO PLASTICIZERS AND EXHIBITS VIRTUALLY NO
LEACHABLES. THE SOLUTION CONTACT LAYER IS A RUBBERIZED COPOLYMER OF ETHYLENE
AND PROPYLENE. THE CONTAINER IS NONTOXIC AND BIOLOGICALLY INERT. THE CONTAINER-SOLUTION
UNIT IS A CLOSED SYSTEM AND IS NOT DEPENDENT UPON ENTRY OF EXTERNAL AIR DURING
ADMINISTRATION. THE CONTAINER IS OVERWRAPPED TO PROVIDE PROTECTION FROM THE
PHYSICAL ENVIRONMENT AND TO PROVIDE AN ADDITIONAL MOISTURE BARRIER WHEN NECESSARY.
1. PADLEY FB: "MAJOR VEGETABLE FATS," THE LIPID
HANDBOOK (GUNSTONE FD, HARWOOD JL, PADLEY FB, EDS.), CHAPMAN AND HALL LTD.,
CAMBRIDGE, UK (1986), PP. 88-9.Last reviewed on RxList: 7/30/2007




Intralipid 20% Drug Description
Intralipid® 20%
(20% I.V. Fat Emulsion)
In Excel® Container
DRUG DESCRIPTION
INTRALIPID® 20% (A 20% INTRAVENOUS FAT EMULSION) IS A STERILE, NON-PYROGENIC
FAT EMULSION PREPARED FOR INTRAVENOUS ADMINISTRATION AS A SOURCE OF CALORIES
AND ESSENTIAL FATTY ACIDS. IT IS MADE UP OF 20% SOYBEAN OIL, 1.2% EGG YOLK PHOSPHOLIPIDS,
2.25% GLYCERIN, AND WATER FOR INJECTION. IN ADDITION, SODIUM HYDROXIDE HAS BEEN
ADDED TO ADJUST THE PH SO THAT THE FINAL PRODUCT PH IS 8. PH RANGE IS 6 TO 8.9.
The soybean oil is a refined natural product consisting of a mixture of neutral
triglycerides of predominantly unsaturated fatty acids with the following structure:







- ARE SATURATED AND UNSATURATED FATTY ACID RESIDUES.
The major component fatty acids are linoleic (44-62%), oleic (19-30%), palmitic
(7-14%), linolenic (4-11%) and stearic (1.4-5.5%)1. These fatty acids
have the following chemical and structural formulas:









PURIFIED EGG PHOSPHATIDES ARE A MIXTURE OF NATURALLY OCCURRING PHOSPHOLIPIDS
WHICH ARE ISOLATED FROM THE EGG YOLK. THESE PHOSPHOLIPIDS HAVE THE FOLLOWING
GENERAL STRUCTURE:









R1C- AND R2C- CONTAIN SATURATED AND UNSATURATED FATTY
ACIDS THAT ABOUND IN NEUTRAL FATS. R3 IS PRIMARILY EITHER THE CHOLINE
OR ETHANOLAMINE ESTER OF PHOSPHORIC ACID.







GLYCERIN IS CHEMICALLY DESIGNATED C3H8O3 AND IS A CLEAR COLORLESS, HYGROSCOPIC
SYRUPY LIQUID. IT HAS THE FOLLOWING STRUCTURAL FORMULA:







INTRALIPID® 20% (A 20% INTRAVENOUSA FAT EMULSION) HAS AN OSMOLALITY OF
APPROXIMATELY 350 MOSMOL/KG WATER (WHICH REPRESENTS 260 MOSMOL/LITER OF EMULSION)
AND CONTAINS EMULSIFIED FAT PARTICLES OF APPROXIMATELY 0.5 MICRON SIZE.
THE TOTAL CALORIC VALUE, INCLUDING FAT, PHOSPHOLIPID AND GLYCERIN, IS 2.0 KCAL
PER ML OF INTRALIPID® 20%. THE PHOSPHOLIPIDS PRESENT CONTRIBUTE 47 MILLIGRAMS
OR APPROXIMATELY 1.5 MMOL OF PHOSPHORUS PER 100 ML OF THE EMULSION.
THE PRIMARY CONTAINER IS MANUFACTURED FROM EXCEL® FILM, A POLYPROPYLENE
BASED MATERIAL COMPRISED OF THREE CO-EXTRUDED LAYERS.
THE PLASTIC CONTAINER IS MADE FROM MULTILAYERED FILM SPECIFICALLY DESIGNED
FOR PARENTERAL DRUGS. IT CONTAINS NO PLASTICIZERS AND EXHIBITS VIRTUALLY NO
LEACHABLES. THE SOLUTION CONTACT LAYER IS A RUBBERIZED COPOLYMER OF ETHYLENE
AND PROPYLENE. THE CONTAINER IS NONTOXIC AND BIOLOGICALLY INERT. THE CONTAINER-SOLUTION
UNIT IS A CLOSED SYSTEM AND IS NOT DEPENDENT UPON ENTRY OF EXTERNAL AIR DURING
ADMINISTRATION. THE CONTAINER IS OVERWRAPPED TO PROVIDE PROTECTION FROM THE
PHYSICAL ENVIRONMENT AND TO PROVIDE AN ADDITIONAL MOISTURE BARRIER WHEN NECESSARY.
1. PADLEY FB: "MAJOR VEGETABLE FATS," THE LIPID
HANDBOOK (GUNSTONE FD, HARWOOD JL, PADLEY FB, EDS.), CHAPMAN AND HALL LTD.,
CAMBRIDGE, UK (1986), PP. 88-9.Last reviewed on RxList: 7/30/2007




Intralipid 20% Drug Description
Intralipid® 20%
(20% I.V. Fat Emulsion)
In Excel® Container
DRUG DESCRIPTION
INTRALIPID® 20% (A 20% INTRAVENOUS FAT EMULSION) IS A STERILE, NON-PYROGENIC
FAT EMULSION PREPARED FOR INTRAVENOUS ADMINISTRATION AS A SOURCE OF CALORIES
AND ESSENTIAL FATTY ACIDS. IT IS MADE UP OF 20% SOYBEAN OIL, 1.2% EGG YOLK PHOSPHOLIPIDS,
2.25% GLYCERIN, AND WATER FOR INJECTION. IN ADDITION, SODIUM HYDROXIDE HAS BEEN
ADDED TO ADJUST THE PH SO THAT THE FINAL PRODUCT PH IS 8. PH RANGE IS 6 TO 8.9.
The soybean oil is a refined natural product consisting of a mixture of neutral
triglycerides of predominantly unsaturated fatty acids with the following structure:







- ARE SATURATED AND UNSATURATED FATTY ACID RESIDUES.
The major component fatty acids are linoleic (44-62%), oleic (19-30%), palmitic
(7-14%), linolenic (4-11%) and stearic (1.4-5.5%)1. These fatty acids
have the following chemical and structural formulas:









PURIFIED EGG PHOSPHATIDES ARE A MIXTURE OF NATURALLY OCCURRING PHOSPHOLIPIDS
WHICH ARE ISOLATED FROM THE EGG YOLK. THESE PHOSPHOLIPIDS HAVE THE FOLLOWING
GENERAL STRUCTURE:









R1C- AND R2C- CONTAIN SATURATED AND UNSATURATED FATTY
ACIDS THAT ABOUND IN NEUTRAL FATS. R3 IS PRIMARILY EITHER THE CHOLINE
OR ETHANOLAMINE ESTER OF PHOSPHORIC ACID.







GLYCERIN IS CHEMICALLY DESIGNATED C3H8O3 AND IS A CLEAR COLORLESS, HYGROSCOPIC
SYRUPY LIQUID. IT HAS THE FOLLOWING STRUCTURAL FORMULA:







INTRALIPID® 20% (A 20% INTRAVENOUSA FAT EMULSION) HAS AN OSMOLALITY OF
APPROXIMATELY 350 MOSMOL/KG WATER (WHICH REPRESENTS 260 MOSMOL/LITER OF EMULSION)
AND CONTAINS EMULSIFIED FAT PARTICLES OF APPROXIMATELY 0.5 MICRON SIZE.
THE TOTAL CALORIC VALUE, INCLUDING FAT, PHOSPHOLIPID AND GLYCERIN, IS 2.0 KCAL
PER ML OF INTRALIPID® 20%. THE PHOSPHOLIPIDS PRESENT CONTRIBUTE 47 MILLIGRAMS
OR APPROXIMATELY 1.5 MMOL OF PHOSPHORUS PER 100 ML OF THE EMULSION.
THE PRIMARY CONTAINER IS MANUFACTURED FROM EXCEL® FILM, A POLYPROPYLENE
BASED MATERIAL COMPRISED OF THREE CO-EXTRUDED LAYERS.
THE PLASTIC CONTAINER IS MADE FROM MULTILAYERED FILM SPECIFICALLY DESIGNED
FOR PARENTERAL DRUGS. IT CONTAINS NO PLASTICIZERS AND EXHIBITS VIRTUALLY NO
LEACHABLES. THE SOLUTION CONTACT LAYER IS A RUBBERIZED COPOLYMER OF ETHYLENE
AND PROPYLENE. THE CONTAINER IS NONTOXIC AND BIOLOGICALLY INERT. THE CONTAINER-SOLUTION
UNIT IS A CLOSED SYSTEM AND IS NOT DEPENDENT UPON ENTRY OF EXTERNAL AIR DURING
ADMINISTRATION. THE CONTAINER IS OVERWRAPPED TO PROVIDE PROTECTION FROM THE
PHYSICAL ENVIRONMENT AND TO PROVIDE AN ADDITIONAL MOISTURE BARRIER WHEN NECESSARY.
1. PADLEY FB: "MAJOR VEGETABLE FATS," THE LIPID
HANDBOOK (GUNSTONE FD, HARWOOD JL, PADLEY FB, EDS.), CHAPMAN AND HALL LTD.,
CAMBRIDGE, UK (1986), PP. 88-9.Last reviewed on RxList: 7/30/2007





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Other reviews about 20% I.V. Fat Emulsion on web:

Learn about the prescription medication Intralipid 20% (20% I.V. Fat Emulsion), drug uses, dosage, side effects, drug interactions, warnings, reviews and patient labeling. Intralipid 20% (20% I.V. Fat Emulsion) Drug Information: Uses ...


INTRALIPID 20% IV Fat Emulsion. 250 mL fill, 250 mL container, NDC# 0338-0519-02 Baxter US Product Catalog - INTRALIPID 20% IV Fat Emulsion


INTRALIPID 20% IV Fat Emulsion. 100 mL fill, 100 mL container, NDC# 0338-0519-48 Baxter US Product Catalog - INTRALIPID 20% IV Fat Emulsion


Intralipid 20% IV fat emulsion - Per L Fractionated soybean oil 10% or 20%, egg yolk phospholipids 12 g, glycerol 22.5 g. Intralipid 20% IV fat emulsion drug information | MIMS Singapore


IV INFUSION ONLY - via peripheral vein or central venous catheter; 10% lipids ... of essential fatty acid deficiency: 500mL of fat emulsion 10% or 250mL of fat emulsion 20% ... fat emulsion


Liposyn (I.V. Fat Emulsion): I.V. fat emulsion for TPN compounding or direct infusion; Available in 10%, 20% and 30% concentrations; Delivers prescribed calories and essential fatty ... Hospira - Liposyn® (I.V. Fat Emulsion)


Fat Emulsion, IV, 20%, 500mL, Glass, SD, Liposyn® III, 12/Case Fat Emulsion, IV, 20%, 500mL, Glass, SD, Liposyn® III, 12/Case ...


Intralipid® 20% (A 20% I.V. Fat Emulsion) Pharmacy Bulk Package should be administered only as a part of a three-in-one or total nutrient admixture via peripheral vein or by ... Intralipid Official FDA information, side effects and uses.


Liposyn II (Intravenous Fat Emulsion) is a sterile ... Both Liposyn II 10% and Liposyn II 20% contain emulsified fat particles ... These are attributable to I.V. therapy in general ... Liposyn II (Intravenous Fat Emulsion) Drug Information: Uses, Side ...


(final concentrations) 6% amino acids, 20% dextrose at 75 mL/h continuous infusion with 20% IV fat emulsion 250 mL/day via piggyback infusion over 12 hours. Self-Assessment Quiz





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